James Hughes may refer to:

Sports

• James Hughes (boxer) (1965–1995), American flyweight boxer
• James Hughes (footballer, born 1885) (1885–1948), English footballer who played for Liverpool
• James Hughes (footballer, born 1911) (1911–?), English footballer who played for Bristol City
• James Hughes (ice hockey) (1906–1983), Canadian professional ice hockey player
• James Hughes (rugby union) (1886–1943), Australian rugby union player
• Jamie Hughes (footballer) (born 1977), English footballer
• Jamie Hughes (darts player) (born 1986), English darts player
• Jay Hughes (1874–1924), also known as Jim Hughes, American Major League Baseball pitcher, who played four seasons from 1898 to 1902
• Jim Hughes (1950s pitcher) (1923–2001), American baseball pitcher
• Jim Hughes (1970s pitcher) (born 1951), American baseball pitcher
• Jim Hughes (Canadian football) (born …Read more on Wikipedia